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phenobarbital will decrease the extent or result of diazepam buccal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on. Potent or moderate CYP3A4 inducers may possibly increase level of diazepam elimination; for that reason, efficacy of diazepam may be lowered.Phenobarbital is usually a barbituric acid derivative f